Bradley R E, Guerrero J, Becker H N, Michael B F, Newcomb K
Am J Vet Res. 1983 Jul;44(7):1329-33.
The anthelmintic spectrum of activity and efficacy of flubendazole, using pigs naturally infected with helminth parasites, were determined in 4 experiments, using 157 pigs. Flubendazole (1.5 mg/kg of body weight) mixed in feed or top-dressed on feed for 5 consecutive days was highly effective as an anthelmintic. This dosage level indicated 100% efficacy against mature Ascaris suum, Oesophagostomum dentatum, Trichuris suis, and Metastrongylus apri. There was 88% efficacy against Strongyloides ransomi and 85% efficacy against Stephanurus dentatus and immature Ascaris suum. There was some activity against Globocephalus sp and Macracanthorhynchus hirudinaceus, but insufficient numbers of these parasites were present to make an accurate assessment.
在4项实验中，使用157头自然感染蠕虫寄生虫的猪，测定了氟苯达唑的驱虫谱及活性和疗效。连续5天将氟苯达唑（1.5毫克/千克体重）混入饲料或撒在饲料表面，作为驱虫药效果极佳。该剂量水平对成熟的猪蛔虫、有齿食道口线虫、猪鞭虫和野猪后圆线虫显示出100%的疗效。对兰氏类圆线虫的疗效为88%，对有齿冠尾线虫和未成熟猪蛔虫的疗效为85%。对球形头属线虫和蛭形巨吻棘头虫有一定活性，但这些寄生虫数量不足，无法进行准确评估。
