[Concentration of plasmin complexes with alpha-2-macroglobulin and alpha-2-antiplasmin in blood plasma and serum].

A methodological approach has been developed for measuring the concentrations of proteinase complexes with their inhibitors in various biological fluids. This approach is based on the use of polyclonal antibodies to the complex complements and their detection by enzyme immunoassay. Appreciable individual differences in the levels of alpha 2-macroglobulin and plasmin in donor blood plasma samples were revealed. Complexes of this inhibitor with plasmin are responsible for about 3% of the total alpha 2-macroglobulin pool in blood plasma and sera.