Lee K T, Tan H H, Li M K, Cheng W S, Rekhraj I R, Foo K T
Department of Urology, Singapore General Hospital.
Singapore Med J. 1995 Apr;36(2):181-4.
One hundred consecutive cases treated by Transurethral Microwave Thermotherapy (TUMT) since October 1991 were analysed to assess its efficacy and safety. Out of these, 28 were in urinary retention. Patients were selected based on Madsen Symptom Score (MSS), Uroflowmetry, Transrectal Ultrasound Scanning (TRUS) plus biopsy and flexible cystoscopy. In the non-retention group, symptomatic improvement was 81%; mean MSS dropped from 13.6 to 2.6 at one year. Objective improvement was less marked: mean peak urine flowrate (PFR) (+45%), mean residual volume (-63%) and mean prostatic volume (-15%). 8.3% had failed TUMT requiring TURP. In the retention group, 79% was able to void freely after TUMT. Fourteen percent underwent TURP. Based on given criteria, the overall response rate for MSS and PFR averaged 71% at 3 months, 72% at 6 months and 84% at 1 year. Sixty-seven percent of patients who responded to a phone interview were satisfied with TUMT treatment. Minimal morbidity was encountered: temporary retention for non-retention group (24%), UTI (9%), haematuria (7%), impotence (2%) and fistula (1%). There was no treatment-related death. The results showed that TUMT is a viable alternative and safe treatment of BPH.
对1991年10月以来接受经尿道微波热疗（TUMT）治疗的100例连续病例进行分析，以评估其疗效和安全性。其中，28例存在尿潴留。患者根据马德森症状评分（MSS）、尿流率测定、经直肠超声扫描（TRUS）加活检以及软性膀胱镜检查进行选择。在无尿潴留组中，症状改善率为81%；一年时平均MSS从13.6降至2.6。客观改善不太明显：平均最大尿流率（PFR）增加45%，平均残余尿量减少63%，平均前列腺体积减少15%。8.3%的患者TUMT治疗失败，需要进行经尿道前列腺切除术（TURP）。在尿潴留组中，79%的患者在TUMT后能够自主排尿。14%的患者接受了TURP。根据既定标准，MSS和PFR的总体缓解率在3个月时平均为71%，6个月时为72%，1年时为84%。在接受电话随访的有反应的患者中，67%对TUMT治疗满意。出现的并发症极少：无尿潴留组有短暂性尿潴留（24%）、泌尿系统感染（9%）、血尿（7%）、阳痿（2%）和尿瘘（1%）。没有与治疗相关的死亡病例。结果表明，TUMT是良性前列腺增生（BPH）一种可行且安全的治疗方法。
