β细胞自身抗原之间的序列相似性。 - Suppr | 超能文献

Sequence similarity between beta-cell autoantigens.

作者信息

Rudy G, Brusic V, Harrison L C, Lew A M

出版信息

Immunol Today. 1995 Aug;16(8):406-7.

Abstract

摘要

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Sequence similarity between beta-cell autoantigens.β细胞自身抗原之间的序列相似性。

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1alpha,25-dihydroxyvitamin D3 induces an autoantigen-specific T-helper 1/T-helper 2 immune shift in NOD mice immunized with GAD65 (p524-543).1α,25-二羟基维生素D3在用GAD65（p524-543）免疫的NOD小鼠中诱导自身抗原特异性辅助性T细胞1/辅助性T细胞2免疫偏移。

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Conversations with GAD.与广泛性焦虑障碍的对话。

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Distinct antigenic features of linear epitopes at the N-terminus and C-terminus of 65 kDa glutamic acid decarboxylase (GAD65): implications for autoantigen modification during pathogenesis.65 kDa谷氨酸脱羧酶（GAD65）N端和C端线性表位的独特抗原特征：对发病机制中自身抗原修饰的意义

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The glutamate decarboxylase and 38KD autoantigens in type 1 diabetes: aspects of structure and epitope recognition.1型糖尿病中的谷氨酸脱羧酶和38KD自身抗原：结构与表位识别方面

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Responses of NOD congenic mice to a glutamic acid decarboxylase-derived peptide.非肥胖糖尿病（NOD）同源基因小鼠对谷氨酸脱羧酶衍生肽的反应。

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Conformational epitopes on the diabetes autoantigen GAD65 identified by peptide phage display and molecular modeling.通过肽噬菌体展示和分子建模鉴定的糖尿病自身抗原GAD65上的构象表位。

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T cells recognize multiple GAD65 and proinsulin epitopes in human type 1 diabetes, suggesting determinant spreading.T细胞在人类1型糖尿病中识别多种GAD65和胰岛素原表位，提示决定簇扩展。

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Front Immunol. 2018 Mar 29;9:623. doi: 10.3389/fimmu.2018.00623. eCollection 2018.

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Abnormal T cell selection on nod thymic epithelium is sufficient to induce autoimmune manifestations in C57BL/6 athymic nude mice.结节性胸腺上皮上异常的T细胞选择足以在C57BL/6无胸腺裸鼠中诱导自身免疫表现。

Proc Natl Acad Sci U S A. 1997 Apr 29;94(9):4598-603. doi: 10.1073/pnas.94.9.4598.