Mlcak R P, Desai M H, Robinson E, McCauley R L, Richardson J, Herndon D N
Shriners Burns Institute, Galveston, Texas, USA.
Burns. 1995 Aug;21(5):337-9. doi: 10.1016/0305-4179(94)00017-4.
Exercise testing enables the simultaneous evaluation of the cardiovascular and respiratory systems' ability to perform gas exchange. The physiological responses to exercise have not been previously reported in the postburn child. This investigation was designed to evaluate residual cardiopulmonary impairment in patients convalescing from severe burns. Spirometry, lung volumes and exercise stress testing were completed on 40 children with a mean time postburn injury of 2.6 +/- 1.9 years and mean burn size of 44 +/- 22 per cent TBSA. Respiratory variables studied during exercise included expired volume, tidal volume and respiratory rate, and physiological dead space/tidal volume (VD/VT) ratios. Stress testing revealed an increased VD/VT ratio consistent with uneven ventilation-perfusion relationships. The data indicate that patients who survive thermal injury may not regain normal cardiopulmonary homeostasis.
运动测试能够同时评估心血管和呼吸系统进行气体交换的能力。此前尚未有关于烧伤后儿童运动生理反应的报道。本研究旨在评估严重烧伤康复期患者心肺功能的残余损伤情况。对40名儿童进行了肺活量测定、肺容量测定和运动压力测试，这些儿童烧伤后平均时间为2.6±1.9年，平均烧伤面积为44±22%TBSA。运动期间研究的呼吸变量包括呼出量、潮气量、呼吸频率以及生理死腔/潮气量（VD/VT）比值。压力测试显示VD/VT比值升高，这与通气-灌注关系不均衡一致。数据表明，热损伤幸存者可能无法恢复正常的心肺稳态。
