Hicks M J, Westerman G H, Flaitz C M, Blankenau R J, Powell G L, Berg J H
Department of Pathology, Texas Children's Hospital, Houston 77030-2399, USA.
Am J Dent. 1995 Feb;8(1):10-4.
To determine the effects of argon laser irradiation (ArI) and topical acidulated phosphate fluoride (APF) treatment on artificial caries formation in root surfaces.
After soft tissue debridement and fluoride-free prophylaxis, the teeth were divided into quarters and acid-resistant varnish was applied, leaving windows of sound root surface exposed. Each tooth received four separate treatments: (1) Control-mesiobuccal quarter; (2) ArI only--mesiolingual quarter; (3) ArI followed by APF- distobuccal quarter; (4) APF followed by ArI-distolingual quarter. ArI was for 10 seconds at 2W (100J/cm2) and APF treatment was for 4 minutes. After artificial lesion formation, sections were prepared and evaluated with polarized light. Mean lesion depths were determined and compared (ANOVA & DMR for a paired design).
Mean lesion depths were: 347 +/- 41 microns--controls; 263 +/- 32 microns--ArI only; 158 +/- 21 microns--ArI followed by APF; and 149 +/- 17 microns -APF followed by ArI. Lesion depths were significantly different (P < 0.05) between the control group and each treatment group, and between ArI only group and either combined APF and ArI groups. No lesion depth difference (P > 0.05) was present between the combined APF and ArI groups. Argon laser irradiation significantly enhanced the resistance of root surfaces to demineralization. Combination of APF treatment with argon laser irradiation provided added protection against a constant artificial caries attack.
确定氩激光照射（ArI）和局部应用酸化磷酸氟（APF）对牙根表面人工龋形成的影响。
在进行软组织清创和无氟预防性清洁后，将牙齿分成四部分，并涂抹抗酸漆，使完好的牙根表面窗口暴露。每颗牙齿接受四种不同的处理：（1）对照——近中颊侧部分；（2）仅ArI——近中舌侧部分；（3）ArI后接APF——远中颊侧部分；（4）APF后接ArI——远中舌侧部分。ArI以2W（100J/cm²）照射10秒，APF处理4分钟。人工龋损形成后，制备切片并用偏振光进行评估。测定并比较平均龋损深度（配对设计采用方差分析和DMR）。
平均龋损深度分别为：对照组347±41微米；仅ArI组263±32微米；ArI后接APF组158±21微米；APF后接ArI组149±17微米。对照组与各处理组之间以及仅ArI组与APF和ArI联合组之间的龋损深度存在显著差异（P<0.05）。APF和ArI联合组之间的龋损深度无差异（P>0.05）。氩激光照射显著增强了牙根表面的抗脱矿能力。APF处理与氩激光照射联合使用可提供额外保护，抵御持续的人工龋攻击。
