Gregg K
Trends Biotechnol. 1995 Oct;13(10):418-21. doi: 10.1016/S0167-7799(00)88995-7.
The rumen bacterium Butyrivibrio fibrosolvens has been genetically modified to detoxify fluoroacetate (a poisonous component of trees and shrubs in Australia, Africa and Central America) and has been shown to persist when it is returned to the rumen. Such bacteria may save animals from poisoning and, therefore, reduce economic losses for livestock industries in those countries. The ability to make genetic changes to rumen bacteria raises important questions about their practicality, and about the environmental factors that must be considered before releasing modified strains. The fluoroacetate-detoxifying bacterium provides an important model by which these issues can be examined.
瘤胃细菌溶纤维丁酸弧菌已通过基因改造来解毒氟乙酸盐（澳大利亚、非洲和中美洲树木和灌木中的一种有毒成分），并且已证明将其重新引入瘤胃后它能持续存在。这类细菌或许能使动物免于中毒，从而减少这些国家畜牧业的经济损失。对瘤胃细菌进行基因改造的能力引发了关于其实用性以及在释放改造菌株之前必须考虑的环境因素的重要问题。这种解毒氟乙酸盐的细菌提供了一个可用于研究这些问题的重要模型。
