Lee L R, Hirst L W, Readshaw G
Department of Surgery, Princess Alexandra Hospital, Woolloongabba, Qld.
Aust N Z J Ophthalmol. 1995 May;23(2):129-33. doi: 10.1111/j.1442-9071.1995.tb00141.x.
To determine the incidence of true unilateral keratoconus on the basis of computerised corneal topography in a group with clinically diagnosed unilateral keratoconus.
Retrospective review of 295 patients with keratoconus identified 51 patients with a provisional diagnosis of unilateral keratoconus. Thirty-one of these patients were re-examined clinically and 21 patients met the criteria for a clinical diagnosis of unilateral keratoconus. Computerised corneal topographic analysis (Tomey TMS) was then performed.
In a group of 21 patients with clinically diagnosed unilateral keratoconus, computerised corneal topographic analysis identified 14 (67%) patients with bilateral keratoconus and seven (33%) patients with true unilateral keratoconus. Contact lens wear had no significant influence (P=0.76) on the topographical diagnosis of keratoconus in the clinically unaffected fellow eye. The estimated incidence of true unilateral keratoconus in the cohort of 295 patients was 4%.
Computerised corneal topography improves sensitivity in detection of true unilateral keratoconus.
基于计算机化角膜地形图确定临床诊断为单侧圆锥角膜的一组患者中真正单侧圆锥角膜的发病率。
对295例圆锥角膜患者进行回顾性研究，确定51例初步诊断为单侧圆锥角膜的患者。其中31例患者接受了临床复查，21例患者符合单侧圆锥角膜的临床诊断标准。然后进行计算机化角膜地形图分析（托米TMS）。
在一组21例临床诊断为单侧圆锥角膜的患者中，计算机化角膜地形图分析确定14例（67%）为双侧圆锥角膜患者，7例（33%）为真正的单侧圆锥角膜患者。佩戴隐形眼镜对临床未受影响的对侧眼圆锥角膜的地形图诊断无显著影响（P = 0.76）。在295例患者队列中，真正单侧圆锥角膜的估计发病率为4%。
计算机化角膜地形图提高了检测真正单侧圆锥角膜的敏感性。
