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与喉罩气道相关的误吸发生率:已发表文献的荟萃分析。

The incidence of aspiration associated with the laryngeal mask airway: a meta-analysis of published literature.

作者信息

Brimacombe J R, Berry A

机构信息

Department of Anaesthesia, Carins Base Hospital, Australia.

出版信息

J Clin Anesth. 1995 Jun;7(4):297-305. doi: 10.1016/0952-8180(95)00026-e.

Abstract

STUDY OBJECTIVE

To determine the incidence of pulmonary aspiration with the laryngeal mask airway (LMA).

DESIGN

A meta-analysis of all published literature on the LMA to September 1993.

MEASUREMENTS AND MAIN RESULTS

All 547 publications were reviewed and coded, and those observational studies in which the LMA was the main form of airway management were analyzed. Pulmonary aspiration was defined as either the presence of bilious secretions or particulate matter in the tracheobronchial tree or, if bronchoscopy was not performed, a postoperative chest radiograph with infiltrates present on preoperative chest radiograph of physical examination. In the study population, there were 3 cases of aspiration in 12,901 patients, and when combined with four independent reports excluded from the detailed analysis, this gave a final incidence of 2 in 10,000. Ten confirmed pulmonary aspiration events from published case reports showed that most cases had one or more predisposing factors. No death of permanent disability occurred.

CONCLUSIONS

The evidence to date suggests that the pulmonary aspiration with the LMA is uncommon and comparable to that for outpatient anesthesia with the face mask and tracheal tube. Meticulous attention to selection of low-risk patients and appropriate operative procedures and avoidance of light anesthesia should reduce the incidence even further.

摘要

研究目的

确定喉罩气道(LMA)导致肺误吸的发生率。

设计

对截至1993年9月所有已发表的关于LMA的文献进行荟萃分析。

测量指标及主要结果

对所有547篇出版物进行了审查和编码,并分析了那些以LMA作为气道管理主要方式的观察性研究。肺误吸的定义为气管支气管树中存在胆汁样分泌物或颗粒物质,或者如果未进行支气管镜检查,则为术后胸部X线片出现术前胸部X线片或体格检查时未见的浸润影。在研究人群中,12901例患者中有3例发生误吸,若将4篇未纳入详细分析的独立报告合并计算,最终发生率为万分之二。已发表病例报告中的10例确诊肺误吸事件表明,大多数病例存在一个或多个易感因素。未发生永久性残疾或死亡。

结论

目前的证据表明,LMA导致的肺误吸并不常见,与面罩和气管导管用于门诊麻醉时的情况相当。对低风险患者的精心选择、合适的手术操作以及避免浅麻醉应可进一步降低发生率。

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