Lacroix D, Nader M A, Savoye C, Klug D, Logier R, Kacet S, Lekieffre J
Cardiology Department, Hôpital Cardiologique, Centre Hospitalier Universitaire de Lille, France.
Br Heart J. 1995 Sep;74(3):277-81. doi: 10.1136/hrt.74.3.277.
To investigate the quantitative relationship, if any, between signal averaged electrocardiographic variables and echocardiographically determined left ventricular mass in hypertensive subjects.
Cohort analytic prospective study.
University hospital.
50 hypertensive subjects selected consecutively from inpatients. Patients older than 75 years, with underlying cardiac disease, with inconclusive echocardiograms with bundle branch block, or in atrial fibrillation were excluded.
Antihypertensive therapy involving 41 patients was continued.
Left ventricular mass calculated in accordance with the standards of the Penn convention. Thirteen criteria derived from combinations of signal averaged electrocardiographic X, Y, and Z Frank orthogonal leads, including voltage criteria, duration, and time-voltage integrals of the QRS complex. Four widely used standard electrocardiographic criteria for detection of left ventricular hypertrophy.
There was no difference in the values for any of the electrocardiographic variables between patients with (n = 29) and without left ventricular hypertrophy (n = 21). The time-voltage integral of QRS in the horizontal plane was the best signal averaged variable related to left ventricular mass (r = 0.33, P = 0.019); however, the correlation with Rodstein voltage was stronger (r = 0.46, P = 0.0009). A positive correlation was also found between left ventricular indexed mass and Rodstein voltage (r = 0.43, P = 0.0019). Stepwise regression analysis revealed Rodstein voltage as the only predictor of indexed mass (P = 0.0019), and Rodstein voltage (P = 0.0022) and body weight (P = 0.011) as the only independent correlates of left ventricular mass.
The relation between electrocardiographic variables and left ventricular mass or indexed mass is of limited value; signal averaged orthogonal leads do not improve this assessment compared with standard electrocardiographic leads.
研究高血压患者中信号平均心电图变量与超声心动图测定的左心室质量之间是否存在定量关系（若存在）。
队列分析前瞻性研究。
大学医院。
从住院患者中连续选取50名高血压患者。排除年龄大于75岁、有潜在心脏病、超声心动图结果不确定且伴有束支传导阻滞或处于心房颤动状态的患者。
41名患者继续接受抗高血压治疗。
根据宾夕法尼亚标准计算左心室质量。从信号平均心电图X、Y和Z弗兰克正交导联组合得出的13项标准，包括电压标准、QRS波群持续时间以及时间 - 电压积分。用于检测左心室肥厚的4项广泛使用的标准心电图标准。
有左心室肥厚的患者（n = 29）和无左心室肥厚的患者（n = 21）之间，任何心电图变量的值均无差异。水平面QRS波群的时间 - 电压积分是与左心室质量相关的最佳信号平均变量（r = 0.33，P = 0.019）；然而，与罗德斯坦电压的相关性更强（r = 0.46，P = 0.0009）。左心室指数质量与罗德斯坦电压之间也存在正相关（r = 0.43，P = 0.0019）。逐步回归分析显示罗德斯坦电压是指数质量的唯一预测因子（P = 0.0019），罗德斯坦电压（P = 0.0022）和体重（P = 0.011）是左心室质量的唯一独立相关因素。
心电图变量与左心室质量或指数质量之间的关系价值有限；与标准心电图导联相比，信号平均正交导联并不能改善这种评估。
