Sutton G, Kalski R S, Lawless M A, Rogers C
Sydney Refractive Surgery Centre, St Leonards, New South Wales, Australia.
Br J Ophthalmol. 1995 Aug;79(8):756-9. doi: 10.1136/bjo.79.8.756.
AIMS/BACKGROUND: Scarring associated with regression of refractive effect can occur after photorefractive keratectomy (PRK) for myopia. The experience of treating these complications is reported.
Eighteen of 285 eyes (6.3%) were retreated with the excimer laser. Age, sex, preoperative primary treatment keratometry, pre-primary treatment, pre-retreatment and post-retreatment spherical equivalents, best corrected and uncorrected visual acuities were recorded and analysed.
At 6 months post-retreatment, the mean spherical equivalent was -2.07 dioptres (D) (SD 4.60 D). This spherical equivalent persisted in eyes followed for 12 months (-2.85D, SD 4.09 D). Nine of 18 eyes (50%) had uncorrected visual acuity of 6/12 (20/40) or better. If retreatment was undertaken within 6.5 months of the initial PRK, then scarring was likely to recur (p = 0.035). Nine of 10 eyes (90%) which had a retreatment spherical equivalent less than two thirds of their primary treatment spherical equivalent were within plus or minus 1.25D from emmetropia after retreatment. Four of 11 eyes (36%) followed for 12 months after retreatment rescarred with further regression.
The data showed that eyes with scarring and regression of myopia should not be treated with PRK within 6 months of the initial procedure. Eyes with the highest percentage of regression towards their initial myopia tend to have a poor response to retreatment.
目的/背景:近视性准分子激光原位角膜磨镶术(PRK)后可出现与屈光效果消退相关的瘢痕形成。本文报告了治疗这些并发症的经验。
285只眼中的18只眼(6.3%)接受了准分子激光再次治疗。记录并分析年龄、性别、术前初次治疗角膜曲率、初次治疗前、再次治疗前及再次治疗后的等效球镜度、最佳矫正视力和未矫正视力。
再次治疗后6个月,平均等效球镜度为-2.07屈光度(D)(标准差4.60 D)。在随访12个月的眼中,该等效球镜度持续存在(-2.85 D,标准差4.09 D)。18只眼中有9只眼(50%)的未矫正视力达到6/12(20/40)或更好。如果在初次PRK后6.5个月内进行再次治疗,则瘢痕形成可能复发(p = 0.035)。再次治疗等效球镜度小于初次治疗等效球镜度三分之二的10只眼中,有9只眼(90%)在再次治疗后等效球镜度与正视眼相差±1.25 D以内。再次治疗后随访12个月的11只眼中,有4只眼(36%)再次出现瘢痕形成且屈光进一步消退。
数据表明,近视瘢痕形成和屈光消退的眼在初次手术6个月内不应接受PRK治疗。向初始近视屈光消退比例最高的眼往往对再次治疗反应较差。