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近视性准分子激光原位角膜磨镶术后瘢痕形成和屈光回退的准分子激光再治疗

Excimer retreatment for scarring and regression after photorefractive keratectomy for myopia.

作者信息

Sutton G, Kalski R S, Lawless M A, Rogers C

机构信息

Sydney Refractive Surgery Centre, St Leonards, New South Wales, Australia.

出版信息

Br J Ophthalmol. 1995 Aug;79(8):756-9. doi: 10.1136/bjo.79.8.756.

Abstract

AIMS/BACKGROUND: Scarring associated with regression of refractive effect can occur after photorefractive keratectomy (PRK) for myopia. The experience of treating these complications is reported.

METHODS

Eighteen of 285 eyes (6.3%) were retreated with the excimer laser. Age, sex, preoperative primary treatment keratometry, pre-primary treatment, pre-retreatment and post-retreatment spherical equivalents, best corrected and uncorrected visual acuities were recorded and analysed.

RESULTS

At 6 months post-retreatment, the mean spherical equivalent was -2.07 dioptres (D) (SD 4.60 D). This spherical equivalent persisted in eyes followed for 12 months (-2.85D, SD 4.09 D). Nine of 18 eyes (50%) had uncorrected visual acuity of 6/12 (20/40) or better. If retreatment was undertaken within 6.5 months of the initial PRK, then scarring was likely to recur (p = 0.035). Nine of 10 eyes (90%) which had a retreatment spherical equivalent less than two thirds of their primary treatment spherical equivalent were within plus or minus 1.25D from emmetropia after retreatment. Four of 11 eyes (36%) followed for 12 months after retreatment rescarred with further regression.

CONCLUSION

The data showed that eyes with scarring and regression of myopia should not be treated with PRK within 6 months of the initial procedure. Eyes with the highest percentage of regression towards their initial myopia tend to have a poor response to retreatment.

摘要

目的/背景:近视性准分子激光原位角膜磨镶术(PRK)后可出现与屈光效果消退相关的瘢痕形成。本文报告了治疗这些并发症的经验。

方法

285只眼中的18只眼(6.3%)接受了准分子激光再次治疗。记录并分析年龄、性别、术前初次治疗角膜曲率、初次治疗前、再次治疗前及再次治疗后的等效球镜度、最佳矫正视力和未矫正视力。

结果

再次治疗后6个月,平均等效球镜度为-2.07屈光度(D)(标准差4.60 D)。在随访12个月的眼中,该等效球镜度持续存在(-2.85 D,标准差4.09 D)。18只眼中有9只眼(50%)的未矫正视力达到6/12(20/40)或更好。如果在初次PRK后6.5个月内进行再次治疗,则瘢痕形成可能复发(p = 0.035)。再次治疗等效球镜度小于初次治疗等效球镜度三分之二的10只眼中,有9只眼(90%)在再次治疗后等效球镜度与正视眼相差±1.25 D以内。再次治疗后随访12个月的11只眼中,有4只眼(36%)再次出现瘢痕形成且屈光进一步消退。

结论

数据表明,近视瘢痕形成和屈光消退的眼在初次手术6个月内不应接受PRK治疗。向初始近视屈光消退比例最高的眼往往对再次治疗反应较差。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d6d8/505242/34b134202734/brjopthal00020-0045-a.jpg

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