磁共振成像显示，一名骨髓发育异常患者的骨髓细胞分布明显不均匀。

Magnetic resonance imaging reveals a markedly inhomogeneous distribution of marrow cellularity in a patient with myelodysplasia.

作者信息

Schick F, Weiss B, Einsele H

机构信息

Department of Diagnostic Radiology, University of Tübingen, Germany.

出版信息

Ann Hematol. 1995 Sep;71(3):143-6. doi: 10.1007/BF01702650.

DOI:10.1007/BF01702650

PMID:7548333

Abstract

A 47-year-old male patient with myelodysplasia showed increasing values of serum lactate dehydrogenase (up to 3500 units/l) and an increasing blast count. Several biopsies (taken from the posterior iliac crest) revealed marked hypocellularity. In contrast, magnetic resonance imaging of the marrow demonstrated an inhomogeneous distribution of marrow with hypocellular and also large hypercellular areas not detected by cytological and histological analysis. A location for biopsy of hypercellular marrow was provided by T1-weighted and water-selective magnetic resonance imaging. The findings in the patient were compared with those in a matched healthy volunteer.

摘要

一名47岁患有骨髓增生异常的男性患者，血清乳酸脱氢酶值不断升高（高达3500单位/升），原始细胞计数也在增加。多次活检（取自髂后嵴）显示明显的细胞减少。相比之下，骨髓的磁共振成像显示骨髓分布不均匀，存在细胞减少区域以及细胞学和组织学分析未检测到的大片细胞增多区域。通过T1加权和水选择性磁共振成像确定了细胞增多骨髓的活检部位。将该患者的检查结果与一名匹配的健康志愿者的结果进行了比较。