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意大利不同教育水平人群的癌症死亡率。

Cancer mortality by educational level in Italy.

作者信息

Faggiano F, Lemma P, Costa G, Gnavi R, Pagnanelli F

机构信息

Department of Hygiene and Community Medicine, University of Turin, Italy.

出版信息

Cancer Causes Control. 1995 Jul;6(4):311-20. doi: 10.1007/BF00051406.

Abstract

Social differences in health concern both ethics and science. From a public health point-of-view, one must assess actual differences and then try to find explanations. This was made possible for the first time for cancer in Italy via nationwide record-linkage between the 1981 census and the national death index. Over the subsequent six months after census, the study-base included 31,000 deaths for cancer and 18 million person-years at risk. Rate ratio (RR) were estimated through a Poisson regression model adjusted by age and geographic area of residence. Educational level was used as social level indicator. Profound social differences were evident for buccal cavity (RR = 3.10 for lowest cf highest educational level), esophagus (RR = 3.00), stomach (RR = 3.43), and larynx (RR = 3.30) among men, and for stomach (RR = 2.25) and uterus (RR = 1.76) among women. Colon (RR = 0.62) and pancreas cancers (RR = 0.65) presented an inverse relationship among men, as did colon (RR = 0.37), breast (RR = 0.56), ovary (RR = 0.45), and melanoma (RR = 0.62) among women. In conclusion, the Italian population at the beginning of the 1980s had large social differences in the risk of dying from cancer, confirming the patterns commonly found in such other countries as Great Britain, France, and New Zealand. Some dissimilarities, useful for hypothesis generation on the mechanisms of inequality, were evident, such as the generally highest social differences found among northern Italian men and among southern Italian women.

摘要

健康方面的社会差异涉及伦理和科学。从公共卫生的角度来看,必须评估实际差异,然后设法找出原因。通过将1981年人口普查与国家死亡指数进行全国范围的记录关联,意大利首次得以对癌症情况进行这样的评估。在普查后的接下来六个月里,研究对象包括31000例癌症死亡病例和1800万人年的风险人群。通过泊松回归模型,根据年龄和居住地理区域进行调整后估计发病率比(RR)。教育水平被用作社会阶层指标。男性中,口腔癌(最低教育水平与最高教育水平相比,RR = 3.10)、食管癌(RR = 3.00)、胃癌(RR = 3.43)和喉癌(RR = 3.30)存在显著的社会差异;女性中,胃癌(RR = 2.25)和子宫癌(RR = 1.76)存在显著差异。男性中结肠癌(RR = 0.62)和胰腺癌(RR = 0.65)呈现负相关,女性中结肠癌(RR = 0.37)、乳腺癌(RR = 0.56)、卵巢癌(RR = 0.45)和黑色素瘤(RR = 0.62)也呈现负相关。总之,20世纪80年代初的意大利人群在死于癌症的风险方面存在很大的社会差异,这证实了在英国、法国和新西兰等其他国家普遍发现的模式。一些差异对于就不平等机制生成假设很有用,比如在意大利北部男性和意大利南部女性中普遍发现的最高社会差异。

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