Scicchitano J, Saccone G T, Baker R A, Roberts-Thomson I C, Toouli J
Department of Surgery, Flinders Medical Centre, Bedford Park, Adelaide, Australia.
J Gastroenterol Hepatol. 1995 May-Jun;10(3):334-6. doi: 10.1111/j.1440-1746.1995.tb01103.x.
The safety of endoscopic manometry of the sphincter of Oddi was evaluated in a prospective survey of 158 consecutive procedures in 126 patients with either unexplained pain after cholecystectomy or idiopathic recurrent pancreatitis. The only complication was that of pancreatitis which was defined as the development of abdominal pain in association with a plasma amylase above the reference range. This occurred in 13 patients (8%) and was more frequent (P = 0.001) when the indication for the procedure was idiopathic recurrent pancreatitis (29%) than unexplained pain (6%). Pancreatitis was also more frequent (P = 0.02) in patients with abnormal manometry (14%) than in those with normal manometry (3%) and occurred at highest frequency (50%) in a subgroup of patients with idiopathic recurrent pancreatitis and sphincter stenosis (high sphincter basal pressure). All episodes of pancreatitis were mild with a median increase in hospital stay of 2 days; no patients died. The risk of pancreatitis after endoscopic manometry is relatively low but increases in patients with abnormal sphincter manometry, particularly those with idiopathic recurrent pancreatitis.
在一项前瞻性调查中，对126例胆囊切除术后原因不明性疼痛或特发性复发性胰腺炎患者连续进行了158次内镜下Oddi括约肌测压术，以评估其安全性。唯一的并发症是胰腺炎，定义为出现腹痛且血浆淀粉酶高于参考范围。13例患者（8%）出现了这种情况，当手术指征为特发性复发性胰腺炎时（29%），其发生率高于原因不明性疼痛时（6%）（P = 0.001）。测压异常的患者中胰腺炎发生率也更高（14%），高于测压正常的患者（3%）（P = 0.02），在特发性复发性胰腺炎合并括约肌狭窄（括约肌基础压力高）的患者亚组中发生率最高（50%）。所有胰腺炎发作均为轻度，住院时间中位数增加2天；无患者死亡。内镜下测压术后胰腺炎的风险相对较低，但括约肌测压异常的患者，尤其是特发性复发性胰腺炎患者，风险会增加。
