活性氧与半胱氨酸、乙酰半胱氨酸和谷胱甘肽的巯基之间的相互作用。
Interactions between reactive oxygen species and sulfhydryl groups of cysteine, acetylcysteine and glutathione.
作者信息
Robak J, Gryglewski R J
机构信息
Department of Pharmacology, Medical College, Jagiellonian University, Kraków, Poland.
出版信息
Pol J Pharmacol. 1995 Jan-Feb;47(1):59-62.
PMID:7550550
Abstract
Oxidative potencies of hydrogen peroxide, superoxide anions or hydroxyl radicals towards sulfhydryl groups of cysteine, acetylcysteine or glutathione were studied. Acetylcysteine was the least susceptible to oxidation by reactive oxygen species. The most vigorous oxidant of sulfhydryl groups was hydrogen peroxide.
摘要
研究了过氧化氢、超氧阴离子或羟基自由基对半胱氨酸、乙酰半胱氨酸或谷胱甘肽巯基的氧化能力。乙酰半胱氨酸对活性氧的氧化最不敏感。巯基最强烈的氧化剂是过氧化氢。
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