[The results of classical in vitro fertilization in male infertility. FIVNAT].

Between 1988 and 1993, FIVNAT register collected data on 1,218 IVF cycles, with less than 500,000 motile and morphologically normal ejaculated spermatozoa per ml on the day of IVF. 700 embryo transfers were performed (57.5% per oocyte retrieval) and the mean number of transferred embryos was 2.4 +/- 1.0. 175 clinical pregnancies were obtained: consequently the clinical pregnancy rate was 14.4% per puncture and 25.0% per transfer. The pregnancy outcome is known for 102 clinical pregnancies (58.3%) and is similar to that of clinical pregnancies obtained from normal sperm. When sperm characteristics display such alterations, numeration lower than 5 millions per ml and total motility lower than 10% impair cleavage rate. The effect of teratozoospermia is not clear, because in this study severe teratozoospermia (> 90%) were associated with high numeration and motility.