Teramoto N, Hayashi K, Miyatani K, Miyake K, Sarker A B, Tadashi Y, Takahashi K, Akagi T, Sunami H, Nawa S
Second Department of Pathology, Okayama University Medical School, Japan.
Pathol Int. 1995 Apr;45(4):315-9. doi: 10.1111/j.1440-1827.1995.tb03463.x.
Right-sided cardiac malignant fibrous histiocytoma (MFH) is extremely rare, and to the authors' knowledge only three cases have been reported. In this study, a case of MFH in the right ventricle, the septum, and the pulmonary valves and artery in a 47 year old male is described. The tumor showed typical pathological features of MFH, such as cellular pleomorphism, storiform pattern and abundant mitoses. Immunohistochemical and electron microscopical findings were compatible with MFH, and excluded the possibility of leiomyosarcoma and angiosarcoma. Whole body examination, including Gallium scintigram, localized the primary site to the heart. The details of this case are presented with a review of the reported cases of cardiac MFH.
右侧心脏恶性纤维组织细胞瘤（MFH）极为罕见，据作者所知，仅报道过3例。在本研究中，描述了一名47岁男性右心室、室间隔、肺动脉瓣及肺动脉发生MFH的病例。肿瘤呈现出MFH典型的病理特征，如细胞多形性、席纹状结构和丰富的核分裂象。免疫组化及电镜检查结果符合MFH，并排除了平滑肌肉瘤和血管肉瘤的可能。包括镓闪烁扫描在内的全身检查将原发部位定位至心脏。现将该病例详情以及已报道的心脏MFH病例予以综述。
