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肿瘤妇科的细胞抑制和激素治疗(作者译)

[Cytostatic and hormonal therapy on oncologic gynecology (author's transl)].

作者信息

Kocijan A, Strzinar V

出版信息

Jugosl Ginekol Opstet. 1978 Mar-Apr;18(2):189-91.

PMID:755124
Abstract

Horones as a therapeutic agent are practically not used in gynecologic oncology, because gynecological malignomas are hormonally independent. Therapeutically succesful in only the use of Progesterone in metastases and relapses of endometrial cancer and of Estrogen in the palliative treatment of cervical cancer relapses. However, significant results are obtained by cytostatic therapy, particularly in carcinomas of the ovary and in choriocarcinomas; the therapy is somewhat less successful in the cancer of the oviduct and vulva, while in the cancer of the cervix and vagina it is not successful at all. Polychemotherapy is recommended because it results in better remissions and is less aggressive.

摘要

激素作为一种治疗药物在妇科肿瘤学中实际上并不常用,因为妇科恶性肿瘤在激素方面是独立的。仅在子宫内膜癌的转移和复发中使用孕酮以及在宫颈癌复发的姑息治疗中使用雌激素治疗取得了成功。然而,细胞抑制疗法取得了显著效果,尤其是在卵巢癌和绒毛膜癌中;在输卵管癌和外阴癌中该疗法的效果稍差,而在宫颈癌和阴道癌中则完全没有效果。推荐采用多药化疗,因为它能带来更好的缓解效果且侵袭性较小。

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