Kirch W, Neuhuber W, Tamm E R
Department of Anatomy, University of Erlangen-Nürnberg, Germany.
Brain Res. 1995 May 29;681(1-2):229-34. doi: 10.1016/0006-8993(95)00299-6.
In human ciliary ganglia, 18% of neurons were in contact with substance P (SP) and 12% with calcitonin gene-related peptide (CGRP) like-immunoreactive (LI) varicose axons. CGRP was colocalized with SP. Numerous SP-LI and CGRP-LI non-varicose nerve fibers were found between the ganglion cells and in nerve trunks that entered the ganglia. Axons immunoreactive for neuropeptide Y (NPY), vasoactive intestinal polypeptide (VIP), tyrosine hydroxylase (TH) or dopamine-beta-hydroxylase (DBH) never contacted neuronal cell bodies. Perikarya of ciliary neurons neither stained for any of the neuropeptides nor for DBH. 23% of ciliary perikarya were TH-immunoreactive. These observations suggest an innervation of human ciliary ganglion neurons by peptidergic primary afferent collaterals presumably of trigeminal origin.
在人睫状神经节中，18%的神经元与P物质（SP）接触，12%的神经元与降钙素基因相关肽（CGRP）样免疫反应性（LI）曲张轴突接触。CGRP与SP共定位。在神经节细胞之间以及进入神经节的神经干中发现了许多SP-LI和CGRP-LI非曲张神经纤维。对神经肽Y（NPY）、血管活性肠肽（VIP）、酪氨酸羟化酶（TH）或多巴胺-β-羟化酶（DBH）免疫反应的轴突从未接触过神经元细胞体。睫状神经元的胞体既未对任何神经肽染色，也未对DBH染色。23%的睫状胞体有TH免疫反应性。这些观察结果提示，人睫状神经节神经元可能由三叉神经起源的肽能初级传入侧支支配。
