Brickell P M, Patel M S
Department of Molecular Pathology, University College London Medical School, UK.
Mol Biotechnol. 1995 Jun;3(3):199-205. doi: 10.1007/BF02789330.
Vectors containing elements of the Epstein-Barr virus genome are used primarily to maintain cloned DNA inserts as plasmids in mammalian cells. However, Epstein-Bar-virus-based vectors have also been valuable tools in the hands of those studying the life cycle of Epstein-Barr virus. In this article, we discuss those characteristics of Epstein-Barr virus and its life cycle that have been used in vector construction and describe methods that are particularly applicable to the use of Epstein-Barr-virus-based vectors.
含有爱泼斯坦-巴尔病毒基因组元件的载体主要用于在哺乳动物细胞中将克隆的DNA插入片段作为质粒进行维持。然而，基于爱泼斯坦-巴尔病毒的载体在研究爱泼斯坦-巴尔病毒生命周期的人员手中也一直是有价值的工具。在本文中，我们讨论了爱泼斯坦-巴尔病毒的那些已用于载体构建的特性及其生命周期，并描述了特别适用于基于爱泼斯坦-巴尔病毒载体使用的方法。
