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酒精性肝病患者的急性胆汁淤积、肝衰竭和脂肪肝。

Acute cholestasis, hepatic failure, and fatty liver in the alcoholic.

作者信息

Morgan M Y, Sherlock S, Scheuer P J

出版信息

Scand J Gastroenterol. 1978;13(3):299-303. doi: 10.3109/00365527809179824.

DOI:10.3109/00365527809179824
PMID:755274
Abstract

Three alcoholic patients are described who presented with acute cholestasis and liver cell failure. In each patient the liver biopsy showed severe fatty change with cholestasis, but without typical alcoholic hepatitis. There was no evidence of extra-hepatic biliary obstruction, although one patient had chronic pancreatitis. Two of the three patients died of hepatic failure, but the third recovered and has remained well while abstaining from alcohol.

摘要

本文描述了三名酒精性肝病患者,他们均表现为急性胆汁淤积和肝细胞衰竭。每位患者的肝活检均显示有严重的脂肪变性伴胆汁淤积,但无典型的酒精性肝炎表现。尽管有一名患者患有慢性胰腺炎,但均无肝外胆管梗阻的证据。三名患者中有两名死于肝衰竭,而第三名患者康复后戒酒,情况一直良好。

相似文献

1
Acute cholestasis, hepatic failure, and fatty liver in the alcoholic.酒精性肝病患者的急性胆汁淤积、肝衰竭和脂肪肝。
Scand J Gastroenterol. 1978;13(3):299-303. doi: 10.3109/00365527809179824.
2
[Acute alcoholic cholestasis].
Rev Clin Esp. 1982 Apr 30;165(2):131-3.
3
[Relationship between cholestasis and hepatic lesions in chronic alcoholics (author's transl)].
Med Clin (Barc). 1982 Jan 25;78(2):52-5.
4
Steatosis, cholestasis, and alkaline phosphatase in alcoholic liver disease.酒精性肝病中的脂肪变性、胆汁淤积和碱性磷酸酶
Am J Dig Dis. 1978 Dec;23(12):1057-60. doi: 10.1007/BF01072878.
5
Factors predictive of liver histopathological appearance in chronic alcoholic pancreatitis with common bile duct stenosis and increased serum alkaline phosphatase.慢性酒精性胰腺炎合并胆总管狭窄及血清碱性磷酸酶升高时肝脏组织病理学表现的预测因素。
Hepatology. 1993 Nov;18(5):1078-81.
6
Alcoholic liver disease in alcoholic chronic pancreatitis: a prospective study.酒精性慢性胰腺炎中的酒精性肝病:一项前瞻性研究。
Ital J Gastroenterol. 1995 Mar;27(2):69-72.
7
Cholestasis in acute alcoholic liver disease.
Lancet. 1977;2(8052-8053):1305-7. doi: 10.1016/s0140-6736(77)90360-9.
8
[Concomitance of hepatic lesions with chronic calcifying pancreatitis in the alcoholic. Study of 60 cases].[酒精性慢性钙化性胰腺炎合并肝脏病变。60例研究]
Arq Gastroenterol. 1983 Jul-Sep;20(3):103-7.
9
Natural history of alcoholic liver disease.酒精性肝病的自然史
Semin Liver Dis. 1981 Aug;1(3):173-8. doi: 10.1055/s-2008-1041745.
10
Significance of microscopic cholangitis in alcoholic liver disease.显微镜下胆管炎在酒精性肝病中的意义。
Gastroenterology. 1978 Dec;75(6):1045-50.

引用本文的文献

1
Alcoholic foamy degeneration and alcoholic fatty liver with jaundice: Often overlooked causes of jaundice and hepatic decompensation that can mimic alcoholic hepatitis.酒精性泡沫样变性和伴有黄疸的酒精性脂肪肝:常被忽视的可酷似酒精性肝炎的黄疸及肝失代偿病因。
Clin Liver Dis (Hoboken). 2016 Jan 21;6(6):145-148. doi: 10.1002/cld.520. eCollection 2015 Dec.
2
Prognostic significance of cholestatic alcoholic hepatitis. VA Cooperative Study Group #119.胆汁淤积性酒精性肝炎的预后意义。退伍军人事务部合作研究小组#119。
Dig Dis Sci. 1990 Jul;35(7):891-6. doi: 10.1007/BF01536804.
3
Clinical significance in alcoholic patients of commonly encountered laboratory test results.
酒精性患者中常见实验室检查结果的临床意义
West J Med. 1992 Mar;156(3):287-94.