Litam P P, Loughran T P
Department of Medicine, Olin Teague Veterans Center, Temple, Texas, USA.
Cancer Invest. 1995;13(5):492-4. doi: 10.3109/07357909509024913.
This is the first case report of Clostridium septicum septicemia in a patient with large granular lymphocyte leukemia. C. septicum infection is highly associated with malignancy and causes a rapidly fatal enterocolitis among patients who are profoundly neutropenic. The need for early recognition and combination of early antibiotic therapy and necessary surgical intervention may help to alter the fulminating nature of C. septicum infection.
这是首例关于大颗粒淋巴细胞白血病患者发生败血梭状芽孢杆菌败血症的病例报告。败血梭状芽孢杆菌感染与恶性肿瘤高度相关,在严重中性粒细胞减少的患者中可引发迅速致命的小肠结肠炎。早期识别以及早期抗生素治疗与必要的手术干预相结合,可能有助于改变败血梭状芽孢杆菌感染的暴发性本质。