Bowman C B, Thompson K P, Stulting R D
Emory Eye Center, Emory University School of Medicine, Department of Ophthalmology, Atlanta, GA, USA.
J Refract Surg. 1995 May-Jun;11(3):202-6.
We utilized videokeratography to determine the frequency of keratoconus suspects in a refractive surgery population, and compared the results of refractive keratotomy in these patients to those of patients with normal corneal topography.
The records of 67 consecutive patients (120 eyes) undergoing refractive keratotomy were reviewed retrospectively. Quantitative measurements of relative inferior corneal steepening (inferior-superior value, I-S value) were obtained from preoperative videokeratography.
Three of 120 eyes (3 of 67 patients, 4.5%) were identified as keratoconus suspects based on I-S (inferior-superior) values greater than +1.74 (range, +1.76 to +2.00), which represented two standard deviations (+/- 0.66) above the mean (+0.42). All three of these eyes achieved postoperative uncorrected visual acuity of 20/30 or better. Of those eyes with normal preoperative topography (I-S value +1.74 or less), 90 of 112 (80%) achieved postoperative uncorrected visual acuity of 20/30 or better, and 105 of 112 (94%) achieved 20/40 or better.
Although long-term follow up is needed to confirm stability of refractive surgery outcome, it appears that keratoconus suspects can obtain acceptable results with refractive keratotomy. Studies on larger patient populations using videokeratography are needed to better define keratoconus, keratoconus suspects, and normal variants of corneal topography and to determine how eyes with abnormal topography respond to refractive keratotomy.
我们利用角膜地形图来确定屈光手术人群中圆锥角膜疑似病例的发生率,并将这些患者的屈光性角膜切开术结果与角膜地形图正常的患者进行比较。
回顾性分析67例(120只眼)连续接受屈光性角膜切开术患者的病历。术前通过角膜地形图获得相对角膜下部陡峭度(下部 - 上部值,I - S值)的定量测量结果。
120只眼中有3只(67例患者中的3例,4.5%)根据I - S(下部 - 上部)值大于 +1.74(范围为 +1.76至 +2.00)被确定为圆锥角膜疑似病例,该值比平均值(+0.42)高出两个标准差(±0.66)。这三只眼中所有术后裸眼视力均达到20/30或更好。术前角膜地形图正常(I - S值为 +1.74或更低)的眼中,112只中有90只(80%)术后裸眼视力达到20/30或更好,112只中有105只(94%)达到20/40或更好。
尽管需要长期随访以确认屈光手术结果的稳定性,但圆锥角膜疑似病例似乎可以通过屈光性角膜切开术获得可接受的结果。需要对更多患者群体进行使用角膜地形图的研究,以更好地定义圆锥角膜、圆锥角膜疑似病例以及角膜地形图的正常变异,并确定角膜地形图异常的眼睛对屈光性角膜切开术的反应。