Li H, Weng X, Li T
Beijing Tropical Medicine Research Institute.
Zhonghua Yi Xue Za Zhi. 1995 Jun;75(6):333-7, 381-2.
The long-term effect of leprosy control was studied in two prefectures of different geographical conditions and socio-economic status. During 1955-1985, the incidence rate in Weifang of Shandong decreased by 94.5% (9.1-0.5/10,000) and became evident after the introduction of MDT in 1986 (0.04/10,000, 1993). In Wenshan of Yunnan, however, it remained at about 20/10,000 before 1980. After the introduction of rifampin plus dapsone in 1979 and fixed duration MDT in 1986, it decreased by 94% (20-1.2/10,000), whereas the detection rate remained constant (+5/100,000). In comparison with the features of new patients detected since 1980, we noted a steady increase of MB rate and voluntary reporting, and a decrease of deformity rate, in the last 8 years in Weifang. It is estimated that by the year 2000 Weifang may have the detection rate of 0.001260/10 thousand and the incidence rate of 0/00757/10 thousand in contrast to the detection rate of 0.2980/10 thousand and the incidence rate of 0.316/10 thousand in Wenshan.
在两个地理条件和社会经济状况不同的地区研究了麻风病防治的长期效果。1955 - 1985年期间,山东潍坊的发病率下降了94.5%(从9.1/万降至0.5/万),1986年引入多药联合化疗后下降趋势明显(1993年为0.04/万)。然而,云南文山在1980年前发病率一直保持在约20/万左右。1979年引入利福平加氨苯砜、1986年引入固定疗程的多药联合化疗后,发病率下降了94%(从20/万降至1.2/万),而发现率保持稳定(+5/10万)。与1980年以来新发现患者的特征相比,我们注意到潍坊在过去8年中多菌型比例和自愿报告率稳步上升,畸残率下降。据估计,到2000年,潍坊的发现率可能为0.001260/万,发病率为0.00757/万,而文山的发现率为0.2980/万,发病率为0.316/万。