Li H Y, Weng X M, Li T, Zheng D Y, Mao Z M, Ran S P, Liu F W
Beijing Tropical Medicine Research Institute, China.
Int J Lepr Other Mycobact Dis. 1995 Jun;63(2):213-21.
In Weifang Prefecture, Shandong Province, and Wenshan Prefecture, Yunnan Province of China, leprosy was highly prevalent in the 1950s. Due to differences in geographical conditions and socioeconomic development, the decline in leprosy prevalence between 1955 and 1993 was 99.5% (10.1 to 0.05/10,000) in Weifang and 93.9% (19.7 to 1.2/10,000) in Wenshan. The decrease in the detection rate was 99.9% (35.2 to 0.05/10,000) in Weifang and 91.7% (69.9 to 5.8/10,000) in Wenshan. The decrease was more apparent in these two prefectures since the implementation of multidrug therapy (MDT) in 1986. Findings such as specific detection rates by age, sex and type, as well as the multibacillary, child, and deformity rates of patients detected since 1980 were studied. Using the detection and prevalence rates between 1980 and 1993, the number of patients until the year 2000 is extrapolated for these two prefectures.
在中国山东省潍坊市和云南省文山州,麻风病在20世纪50年代高度流行。由于地理条件和社会经济发展的差异,1955年至1993年期间,潍坊市麻风病患病率下降了99.5%(从10.1/万降至0.05/万),文山州下降了93.9%(从19.7/万降至1.2/万)。潍坊市的发现率下降了99.9%(从35.2/万降至0.05/万),文山州下降了91.7%(从69.9/万降至5.8/万)。自1986年实施多药联合化疗(MDT)以来,这两个地区的下降更为明显。研究了1980年以来按年龄、性别和类型划分的特定发现率,以及患者的多菌型、儿童和残疾率。利用1980年至1993年的发现率和患病率,推算出这两个地区到2000年的患者数量。