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A carboxylesterase from the parasitic nematode Ascaris suum homologous to the intestinal-specific ges-1 esterase of Caenorhabditis elegans.

作者信息

Azzaria M, Henzel W J, McGhee J D

机构信息

Department of Medical Biochemistry, University of Calgary, Alberta, Canada.

出版信息

Comp Biochem Physiol B Biochem Mol Biol. 1994 Oct-Nov;109(2-3):225-36. doi: 10.1016/0305-0491(94)90006-x.

DOI:10.1016/0305-0491(94)90006-x
PMID:7553343
Abstract

We have identified a carboxylesterase in A. suum that appears to be the homolog of the gut-specific C. elegans ges-1 enzyme. The A. suum esterase was purified and its N-terminal sequence found to be 50% identical to the C. elegans ges-1 protein. We have used isoelectric focusing analysis to demonstrate that, unlike the C. elegans ges-1 esterase, the A. suum enzyme is not restricted to the gut but is expressed in a wide range of tissues.

摘要

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