Up-regulation of resistance-related proteins in human lung tumors with poor vascularization.
作者信息
Koomägi R, Mattern J, Volm M
机构信息
Department of Radiology and Oncology, Tartu University, Estonia.
出版信息
Carcinogenesis. 1995 Sep;16(9):2129-33. doi: 10.1093/carcin/16.9.2129.
PMID:7554065
Abstract
Microvessel density was investigated by immunostaining endothelial cells for factor VIII antigen in 84 non-small cell lung carcinomas and compared with the expression of several resistance-related proteins. Glutathione S-transferase-pi, thymidylate synthase, metallothionein and, with limitations, P-glycoprotein were overexpressed in tumors with poor vascularization.
摘要
Zotero 插件