Lafont P, Guy-Crotte O, Paulin C, Galvain D, Mertani S, Figarella C, Barbier Y
Centre hospitalier Lyon-Sud, Pierre-Bénite, France.
Clin Chim Acta. 1995 Mar 31;235(2):197-206. doi: 10.1016/0009-8981(95)06030-x.
An immunoradiometric assay using two monoclonal antibodies directed to human trypsin 1 was developed for measuring trypsin(ogen) in biological fluids. The assay is different from other assays in that it is specific for cationic trypsinogen and does not recognize the alpha-1-proteinase inhibitor-trypsin complex. It can be used as a complement to classical immunoassays to characterize trypsinogen activation in pathological cases. The evaluation and the specificity of the assay are presented.
开发了一种使用两种针对人胰蛋白酶1的单克隆抗体的免疫放射分析方法，用于测量生物体液中的胰蛋白酶（原）。该分析方法与其他分析方法不同，因为它对阳离子胰蛋白酶原具有特异性，并且不识别α-1-蛋白酶抑制剂-胰蛋白酶复合物。它可以作为经典免疫分析的补充，用于表征病理情况下的胰蛋白酶原激活。本文介绍了该分析方法的评估和特异性。
