Chabasse D, Pollet E, D'Hilaire I, Goethals G, Robert R
Bull Soc Pathol Exot Filiales. 1978 Nov-Dec;71(6):446-50.
Fifty patients stricken by giardiosis were treated by a single dose administration of Tinidazole -- 50 mg./kg. for children and 2 g. for adults per os. Fifteen days after treatment, 84 0/0 of the patients had negative coprologic exams for giardiosis. The product was well-tolerated by the digestive tract as was demonstrated by a coprologic examination for digested food reside; however, minor digestive inconveniences were noted in 87 0/0 of the patients. There were no perturbations of hematologic or hepatic tests. This product would thus appear to be a treatment of choice in the management of giardiosis.
五十名贾第虫病患者接受了替硝唑单剂量口服治疗,儿童剂量为50毫克/千克,成人剂量为2克。治疗后15天,84%的患者贾第虫病粪便检查呈阴性。粪便检查显示该产品在消化道耐受性良好;然而,87%的患者出现了轻微的消化系统不适。血液学或肝脏检查未发现异常。因此,该产品似乎是治疗贾第虫病的首选药物。