糖尿病性神经病变中的身体摇摆
Body sway in diabetic neuropathy.
作者信息
Uccioli L, Giacomini P G, Monticone G, Magrini A, Durola L, Bruno E, Parisi L, Di Girolamo S, Menzinger G
机构信息
Department of Endocrinology and Internal Medicine, University of Rome Tor Vergata, Italy.
出版信息
Diabetes Care. 1995 Mar;18(3):339-44. doi: 10.2337/diacare.18.3.339.
OBJECTIVE
To evaluate the influence of peripheral neuropathy on body sway assessed by posturography.
RESEARCH DESIGN AND METHODS
The age-matched study subjects included 10 insulin-dependent diabetes mellitus (IDDM) patients with peripheral neuropathy (DN), 23 IDDM patients without peripheral neuropathy (D) according to the San Antonio Consensus Conference guidelines, and 21 control subjects (C). All subjects with symptoms and/or clinical signs of postural instability were excluded from the study.
RESULTS
The trace surface was significantly larger in the DN than in the C and D groups (P < 0.05), and the trace length was longer in the DN than in the C and D groups (P < 0.01). Mean velocity was faster in the DN than in the other two groups (P < 0.001). A direct relationship was found between the parameters of posturography and some parameters of the nerve conduction velocity.
CONCLUSIONS
Diabetic patients with peripheral neuropathy demonstrate a relative deficit in their ability to maintain posture. Posturography allows an early disclosure of the failure of postural control.
目的
评估周围神经病变对姿势描记法所测定的身体摆动的影响。
研究设计与方法
根据圣安东尼奥共识会议指南，年龄匹配的研究对象包括10名患有周围神经病变（DN）的胰岛素依赖型糖尿病（IDDM）患者、23名无周围神经病变的IDDM患者（D）以及21名对照者（C）。所有有姿势不稳症状和/或临床体征的受试者均被排除在研究之外。
结果
DN组的轨迹面积显著大于C组和D组（P < 0.05），DN组的轨迹长度长于C组和D组（P < 0.01）。DN组的平均速度快于其他两组（P < 0.001）。姿势描记法参数与神经传导速度的一些参数之间存在直接关系。
结论
患有周围神经病变的糖尿病患者在维持姿势的能力方面表现出相对缺陷。姿势描记法能够早期发现姿势控制的失败。
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