[光化学疗法与白内障形成]
[Photochemotherapy and cataract formation].
作者信息
Koch H R
出版信息
Derm Beruf Umwelt. 1978;26(5):162-5.
PMID:755656
Abstract
According to the literature combined treatment with 8-MOP and UVA has induced ocular damage in animals. Similar changes in humans on photochemotherapy have not yet been reported and therapeutic doses are considerably lower than the doses that proved toxic for the animal eye. The present paper reviews pertinent literature on the subject and discusses the conditions under which photochemotherapy for psoriasis seems acceptable in view of present day knowledge.
摘要
根据文献记载，8-甲氧基补骨脂素（8-MOP）与紫外线A（UVA）联合治疗已在动物身上引发眼部损伤。光化学疗法在人类身上尚未报告有类似变化，且治疗剂量远低于对动物眼睛有毒性的剂量。本文回顾了该主题的相关文献，并根据当前知识讨论了在何种情况下银屑病光化学疗法似乎是可接受的。
相似文献
1
[Photochemotherapy and cataract formation].[光化学疗法与白内障形成]
Derm Beruf Umwelt. 1978;26(5):162-5.
2
[Could PUVA therapy and solar lights provoke ocular lesions?].补骨脂素加紫外线A光疗法（PUVA疗法）和太阳灯能引发眼部病变吗？
Bull Soc Belge Ophtalmol. 1979;185:111-7.
3
Photochemotherapy and the eye: photoprotective factors.光化学疗法与眼睛：光保护因子
Trans Am Ophthalmol Soc. 1980;78:243-54.
4
Lenticular psoralen photoproducts and cataracts of a PUVA-treated psoriatic patient.一名接受补骨脂素加长波紫外线（PUVA）治疗的银屑病患者的晶状体补骨脂素光产物与白内障
Arch Dermatol. 1985 Oct;121(10):1307-8.
5
8-methoxypsoralen and long ultraviolet effects on the rat lens: experiments with high dosage.
Graefes Arch Clin Exp Ophthalmol. 1982;218(4):193-9. doi: 10.1007/BF02150094.
6
[Oral photochemotherapy (author's transl)].[口服光化学疗法（作者译）]
Wien Klin Wochenschr Suppl. 1977;75:1-30.
7
Absence of cataract ten years after treatment with 8-methoxypsoralen.使用8-甲氧基补骨脂素治疗十年后未出现白内障。
Acta Derm Venereol. 1980;60(1):79-80.
8
Safety and therapeutic effectiveness of selected psoralens in psoriasis.特定补骨脂素在银屑病中的安全性和治疗效果
Natl Cancer Inst Monogr. 1984 Dec;66:159-64.
9
A retrospective study of cataract formation in 96 patients treated with PUVA.一项对96例接受光化学疗法（PUVA）治疗患者的白内障形成情况的回顾性研究。
Acta Derm Venereol. 1982;62(5):444-6.
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