肥大细胞胆管病：硬化性胆管炎的另一个病因。

Mast cell cholangiopathy: another cause of sclerosing cholangitis.

作者信息

Baron T H, Koehler R E, Rodgers W H, Fallon M B, Ferguson S M

机构信息

Department of Medicine, University of Alabama at Birmingham Medical Center, USA.

出版信息

Gastroenterology. 1995 Nov;109(5):1677-81. doi: 10.1016/0016-5085(95)90658-4.

DOI:10.1016/0016-5085(95)90658-4

PMID:7557153

Abstract

A 75-year-old woman with known systemic mastocytosis presented with abdominal pain, ascites, and bile duct thickening on computed tomography and ultrasonography. A liver biopsy specimen showed infiltration with mast cells. Endoscopic retrograde cholangiography showed ductal changes compatible with those found in primary sclerosing cholangitis. Brush cytology of the intrahepatic bile ducts confirmed mast cell infiltration. Systemic mastocytosis can infiltrate the biliary system, producing a cholangiopathy radiographically similar to primary sclerosing cholangitis.

摘要

一名75岁的已知患有系统性肥大细胞增多症的女性，出现腹痛、腹水，计算机断层扫描和超声检查显示胆管增厚。肝脏活检标本显示有肥大细胞浸润。内镜逆行胆管造影显示导管改变与原发性硬化性胆管炎所见相符。肝内胆管刷检细胞学检查证实有肥大细胞浸润。系统性肥大细胞增多症可浸润胆道系统，产生影像学上与原发性硬化性胆管炎相似的胆管病。