Raoul J L, Le Prisé E, Meunier B, Julienne V, Etienne P L, Gosselin M, Launois B
Centre F. Marquis, Rennes, France.
Gut. 1995 Aug;37(2):174-6. doi: 10.1136/gut.37.2.174.
Postoperative recurrences are common after resection for oesophageal cancer. From January 1986 to September 1993 31 patients (30 males, one female, mean (SD) age: 57.5 (8.8) years) were treated for locoregional recurrence (n = 24), metastases (n = 6) or both (n = 1) occurring 15.0 (12.6) months after initial surgery. Radiotherapy and chemotherapy were combined in all cases. Symptomatic improvement was seen in 23 cases (74%) and lasted (excluding treatment period) for 6.3 (4) months. Objective tumoral response was seen in 20 patients (65%) including eight (26%) complete responses. Survival rates were at respectively six months, one, two, and three years: 70.7%, 47.1%, 17.1%, 4.3%. In conclusion, these results show that combined therapy could have a beneficial symptomatic effect and can be associated with prolonged survival in patients with postoperative recurrences of oesophageal cancer.
食管癌切除术后复发很常见。1986年1月至1993年9月，31例患者（30例男性，1例女性，平均（标准差）年龄：57.5（8.8）岁）接受了局部区域复发（n = 24）、转移（n = 6）或两者皆有（n = 1）的治疗，这些复发或转移发生在初次手术后15.0（12.6）个月。所有病例均采用放疗和化疗联合治疗。23例（74%）患者症状改善，（不包括治疗期）持续6.3（4）个月。20例（65%）患者出现客观肿瘤反应，其中8例（26%）完全缓解。6个月、1年、2年和3年生存率分别为：70.7%、47.1%、17.1%、4.3%。总之，这些结果表明联合治疗对症状改善有益，并且可延长食管癌术后复发患者的生存期。
