Hunt D M, Cowing J A, Patel R, Appukuttan B, Bowmaker J K, Mollon J D
Department of Molecular Genetics, University of London, United Kingdom.
Genomics. 1995 Jun 10;27(3):535-8. doi: 10.1006/geno.1995.1088.
The sequences of the blue cone photopigments in the talapoin monkey (Miopithecus talapoin), an Old World primate, and in the marmoset (Callithrix jacchus), a New World monkey, are presented. Both genes are composed of 5 exons separated by 4 introns. In this respect, they are identical to the human blue gene, and intron sizes are also similar. Based on the level of amino acid identity, both monkey pigments are members of the S branch of pigments. Alignment of these sequences with the human gene requires the insertion/deletion of two separate codons in exon 1. The silent site divergence between these primate blue genes indicates a separation of the Old and New World primate lineages around 43 million years ago.
本文展示了旧大陆灵长类动物——塔那河红疣猴（Miopithecus talapoin）和新大陆猴——狨猴（Callithrix jacchus）的蓝色视锥色素序列。这两个基因均由5个外显子组成，中间间隔4个内含子。在这方面，它们与人类蓝色基因相同，内含子大小也相似。基于氨基酸同一性水平，两种猴色素均属于色素S分支。这些序列与人类基因的比对需要在外显子1中插入/缺失两个单独的密码子。这些灵长类动物蓝色基因之间的沉默位点差异表明，旧大陆和新大陆灵长类谱系在约4300万年前发生了分化。
