Skaria A M, Chavaz P, Hauser C
Clinique et Policlinique de Dermatologie et Vénéréologie, Hôpital Cantonal Universitaire de Genève.
Hautarzt. 1995 Aug;46(8):579-81. doi: 10.1007/s001050050303.
We present a 58-year-old patient with disseminated aspergillosis and metastatic panniculitis. He suffered from agranulocytosis and blastic transformation of a myelodysplastic syndrome. The skin lesion showed a single subcutaneous inflammatory nodule, which was clearly shown by histolog to be of embolic origin. This clinical presentation has not previously been described. Disseminated aspergillosis is found mainly in immunocompromised and neutropenic patients and the mortality is high. The present case demonstrates how histological examination together with skin biopsy culture can allow the diagnosis.
我们报告一例58岁患有播散性曲霉病和转移性脂膜炎的患者。他患有粒细胞缺乏症以及骨髓增生异常综合征的原始细胞转化。皮肤病变表现为单个皮下炎性结节，组织学检查明确显示其为栓子来源。这种临床表现此前尚未见报道。播散性曲霉病主要见于免疫功能低下和中性粒细胞减少的患者，死亡率很高。本病例展示了组织学检查与皮肤活检培养如何有助于诊断。
