Charles A K, Caul E O, Porter H J, Oakhill A
Department of Paediatric Pathology, Royal Children's Hospital, Bristol.
J Clin Pathol. 1995 Aug;48(8):779-81. doi: 10.1136/jcp.48.8.779.
A case of disseminated adenovirus type 32 infection causing severe hepatitis, gastrointestinal ulceration and also with respiratory involvement is reported in a bone marrow transplant recipient. Typical viral inclusions were seen in the postmortem histological sections and adenovirus infection was confirmed using in situ hybridisation and isolation of adenovirus type 32 from separate organs at necropsy. This is the first case in which adenovirus 32 was the cause of fatal disseminated disease in a bone marrow transplant recipient.
据报道，一名骨髓移植受者发生了32型腺病毒播散性感染，导致严重肝炎、胃肠道溃疡，还累及呼吸道。尸检组织学切片中可见典型的病毒包涵体，通过原位杂交以及尸检时从不同器官分离出32型腺病毒，证实了腺病毒感染。这是首例32型腺病毒导致骨髓移植受者发生致命播散性疾病的病例。
