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Effects of theophylline on renal insufficiency in neonates with respiratory distress syndrome.

作者信息

Huet F, Semama D, Grimaldi M, Guignard J P, Gouyon J B

机构信息

Service de Pédiatrie 2, Hpital d'Enfants, CHRU de Dijon, France.

出版信息

Intensive Care Med. 1995 Jun;21(6):511-4. doi: 10.1007/BF01706205.

DOI:10.1007/BF01706205
PMID:7560495
Abstract

We report here 6 cases of critically ill newborn infants with both RDS and acute renal insufficiency, unresponsive to conventional treatment (furosemide, dopamine). Theophylline, an adenosine antagonist, has been shown to prevent hypoxemia-induced renal insufficiency in rabbits and our patients thus received compassionately a low-dose of theophylline (1 mg . kg-1 i.v.). Urinary water excretion and creatinine clearances increased significantly in 5 out of 6 neonates, thus suggesting a beneficial role of theophylline in neonatal prerenal failure.

摘要

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本文引用的文献

1
Causes of increased renal echogenicity in pediatric patients.小儿患者肾回声增强的原因。
Pediatrics. 1983 Dec;72(6):840-6.
2
Interactions between adenosine and angiotensin II in controlling glomerular filtration.腺苷与血管紧张素II在控制肾小球滤过中的相互作用。
Am J Physiol. 1985 Mar;248(3 Pt 2):F340-6. doi: 10.1152/ajprenal.1985.248.3.F340.
3
Continuous renal prosthetic therapy in acute renal failure: an overview.急性肾衰竭的连续性肾脏替代治疗：综述
氨茶碱与新生儿全胃肠外营养的相容性。
J Pediatr Pharmacol Ther. 2008 Apr;13(2):76-9. doi: 10.5863/1551-6776-13.2.76.
4
Diuretics for respiratory distress syndrome in preterm infants.利尿剂用于早产儿呼吸窘迫综合征
Cochrane Database Syst Rev. 2011 Dec 7;2011(12):CD001454. doi: 10.1002/14651858.CD001454.pub3.
5
Additive diuretic response of concurrent aminophylline and furosemide in children: a case series and a brief literature review.同时使用氨茶碱和呋塞米的儿童利尿效果增强：病例系列和文献复习。
J Anesth. 2012 Feb;26(1):118-23. doi: 10.1007/s00540-011-1250-0. Epub 2011 Oct 18.
6
Acute renal failure in neonates.新生儿急性肾衰竭
Indian J Pediatr. 2008 Apr;75(4):385-91. doi: 10.1007/s12098-008-0043-4. Epub 2008 May 18.
7
A randomised, double blind, placebo controlled trial of the effect of theophylline in prevention of vasomotor nephropathy in very preterm neonates with respiratory distress syndrome.一项关于茶碱对患有呼吸窘迫综合征的极早产儿预防血管舒缩性肾病效果的随机、双盲、安慰剂对照试验。
Arch Dis Child Fetal Neonatal Ed. 2006 Mar;91(2):F80-4. doi: 10.1136/adc.2005.073650. Epub 2005 Oct 4.
8
Prophylactic theophylline to prevent renal dysfunction in newborns exposed to perinatal asphyxia--a study in a developing country.预防性使用茶碱预防围产期窒息新生儿的肾功能障碍——一项在发展中国家的研究。
Pediatr Nephrol. 2005 Sep;20(9):1249-52. doi: 10.1007/s00467-005-1980-z. Epub 2005 Jun 10.
Pediatr Clin North Am. 1987 Feb;34(1):165-85. doi: 10.1016/s0031-3955(16)36187-9.
4
Acute oliguria in preterm infants with hyaline membrane disease: interaction of dopamine and furosemide.患有透明膜病的早产儿急性少尿：多巴胺与呋塞米的相互作用
Acta Paediatr Scand. 1986 May;75(3):420-4. doi: 10.1111/j.1651-2227.1986.tb10224.x.
5
Theophylline prevents the hypoxemia-induced renal hemodynamic changes in rabbits.
Kidney Int. 1988 Jun;33(6):1078-83. doi: 10.1038/ki.1988.114.
6
Drugs and acute renal insufficiency in the neonate.
Biol Neonate. 1986;50(4):177-81. doi: 10.1159/000242597.
7
Renal function in respiratory distress syndrome.
J Pediatr. 1976 May;88(5):845-50. doi: 10.1016/s0022-3476(76)81129-8.
8
Glomerular filtration rate in the first three weeks of life.
J Pediatr. 1975 Aug;87(2):268-72. doi: 10.1016/s0022-3476(75)80600-7.
9
Tissue content of adenosine, inosine and hypoxanthine in the rat kidney after ischemia and postischemic recirculation.大鼠肾脏缺血及缺血后再灌注时腺苷、肌苷和次黄嘌呤的组织含量
Pflugers Arch. 1977 Oct 19;371(1-2):45-9. doi: 10.1007/BF00580771.