Biondi E, Grandori F
Scand Audiol. 1978;7(2):81-7. doi: 10.3109/01050397809043136.
The present research was undertaken to approach the formation of the Brainstem Evoked Response (BSER) by means of modelling techniques similar to those previously successfully adopted to interpret the generation of the Auditory Nerve Action Potential. The definition of a model intended to reproduce the compound electrical response of a given ensemble of neural units, firing after stimulation, is taken as the basic constituent for the formulation of the complete model. The activity of the primary auditory neurons is assumed to be the input to the BSER model; then, a simplified structure for the connections among the neural complexes contributing to the BSER is proposed to account for monaurally evoked, homolaterally recorded responses. Computer simulations of the model show a satisfactory degree of approximation between the experimental data taken as reference and the final output, in spite of the rather small number of parameters and the simplicity of the structure used. Even though this work has to be considered as preliminary in character, at least in certain respects, some applicative implications of the present approach can be outlined.
本研究旨在通过类似于先前成功用于解释听神经动作电位产生的建模技术,来探讨脑干听觉诱发电位(BSER)的形成。旨在重现给定神经单元集合在刺激后放电的复合电反应的模型定义,被视为构建完整模型的基本要素。假定初级听觉神经元的活动是BSER模型的输入;然后,提出了一种用于构成BSER的神经复合体之间连接的简化结构,以解释单耳诱发、同侧记录的反应。尽管所使用的参数数量相当少且结构简单,但该模型的计算机模拟显示,作为参考的实验数据与最终输出之间具有令人满意的近似程度。尽管这项工作在某些方面至少必须被视为具有初步性质,但仍可概述本方法的一些应用意义。