Le Mer Y
Service d'Ophtalmologie, Montreuil.
J Fr Ophtalmol. 1995;18(5):366-72.
Thanks to their physical properties, could perfluorocarbon liquids (PFCL) be useful during vitrectomy for severe cases of proliferative diabetic vitreo-retinopathy (PDVR)?
Among 120 vitrectomies for PDVR performed in a period of time from August 1992 to July 1993, we reviewed 24 cases with a minimal follow-up of six months for which we have used PFCL as intraoperative tool. Among these eyes, three (12%) were preoperatively attached, seven (29%) presented with a tractional retinal detachment sparing the macular area and 14 (59%) with a retinal detachment involving the macula. The indication for PFCL injection was either to flatten the retina in case of iatrogenic tear or retinotomy (15/24 eyes) or to stop a bleeding coming from the optic disc (9/24). The aim was to allow a good laser endophotocoagulation in all the cases and to inject an intraocular tamponade on a reattached retina if needed. As final tamponade, silicone oil was used in 10 eyes, gas in nine eyes and none in five eyes.
At the end of the study, 20 (83%) eyes had a totally reattached retina and four (17%) a detached retina. The postoperative compared to the preoperative visual acuity was improved in 13 eyes (54%), unchanged in seven eyes (30%) and decreased in four eyes (16%). In one case (4%), some droplets of PFCL were noticed in the vitreous cavity, under the silicone oil bubble, with a good clinical tolerance. No specific complication of PFCL injection could be found in the 23 other eyes.
In some selected cases of severe PDVR, the use of PFCL may help to flatten the retina, to stop bleeding from the optic disc and to perform a good endolaser photocoagulation. This allows to achieve good anatomical and visual results with few specific complications.
鉴于全氟碳化合物液体(PFCL)的物理特性,其在严重增殖性糖尿病玻璃体视网膜病变(PDVR)的玻璃体切除术中是否有用?
在1992年8月至1993年7月期间进行的120例PDVR玻璃体切除术当中,我们回顾了24例至少随访6个月的病例,这些病例术中使用了PFCL。在这些眼中,3只眼(12%)术前视网膜附着,7只眼(29%)出现黄斑区未受累的牵引性视网膜脱离,14只眼(59%)出现累及黄斑的视网膜脱离。PFCL注射的指征要么是在医源性撕裂或视网膜切开的情况下使视网膜变平(15/24只眼),要么是阻止来自视盘的出血(9/24)。目的是在所有病例中进行良好的激光眼内光凝,并在需要时向复位的视网膜注入眼内填充剂。作为最终填充剂,10只眼使用了硅油,9只眼使用了气体,5只眼未使用。
研究结束时,20只眼(83%)视网膜完全复位,4只眼(17%)视网膜脱离。与术前相比,13只眼(54%)术后视力提高,7只眼(30%)不变,4只眼(16%)下降。1例(4%)在玻璃体腔硅油泡下方发现一些PFCL液滴,临床耐受性良好。其他23只眼中未发现PFCL注射的特定并发症。
在一些严重PDVR的特定病例中,使用PFCL可能有助于使视网膜变平、阻止视盘出血并进行良好的眼内激光光凝。这能够在很少有特定并发症的情况下获得良好的解剖和视觉效果。