Cavallari A, Vivarelli M, D'Errico A, Bellusci R, Scarani P, DeRaffele E, Nardo B, Gozzetti G
Second Department of Surgery, University of Bologna, S. Orsola Hospital, Italy.
J Hepatol. 1995 Jun;22(6):685-90. doi: 10.1016/0168-8278(95)80224-x.
A 32-year-old man who had undergone liver transplantation for fulminant hepatitis due to HBV infection developed fatal acute necrotizing pancreatitis on the 60th post-transplant day, while showing signs of intense viral replication. Immunohistochemistry and in situ hybridization of the pancreas following autopsy showed the presence of HBsAG and HBV-DNA in the cytoplasm of acinar cells, together with the picture of necrotizing pancreatitis. Clinical and histological features seem to indicate that pancreatitis was directly caused by HBV infection.
