McGuire T R
Department of Biological Sciences, Nelson Biological Laboratories, Rutgers University, Piscataway, NJ 08855-1059, USA.
J Homosex. 1995;28(1-2):115-45. doi: 10.1300/J082v28n01_08.
Genetic analysis of behavioral differences among human beings requires both careful experimental design and appropriate genetic models. Any genetic study must be (1) valid and precise measures of individual differences, (2) appropriate methods to ascertain biological relationships, (3) research subjects who have been randomly recruited, (4) appropriate sample sizes, and (5) appropriate genetic models to interpret the data. In addition, the researchers must exercise caution in interpreting biosocial effects from the observed phenotypic correlations. To date, all studies of the genetic basis of sexual orientation of men and women have failed to meet one or more or any of the above criteria.
对人类行为差异进行基因分析,既需要精心设计实验,也需要合适的基因模型。任何基因研究都必须具备:(1)对个体差异进行有效且精确的测量;(2)确定生物学关系的恰当方法;(3)随机招募的研究对象;(4)合适的样本量;(5)用于解释数据的恰当基因模型。此外,研究人员在从观察到的表型相关性来解释生物社会效应时必须谨慎。迄今为止,所有关于男性和女性性取向基因基础的研究都未能满足上述一项或多项甚至全部标准。