Dowell S F, Török T J, Thorp J A, Hedrick J, Erdman D D, Zaki S R, Hinkle C J, Bayer W L, Anderson L J
Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA.
J Infect Dis. 1995 Oct;172(4):1076-9. doi: 10.1093/infdis/172.4.1076.
A suspected nosocomial outbreak of parvovirus B19 infection in a maternity ward was investigated in February 1994. Questionnaires were administered and sera collected from maternity ward staff (n = 91), other ward staff in the same hospital (n = 101), and maternity ward staff at a nearby hospital (n = 81). Blood donors (n = 265) were used as community controls. Recent infection (parvovirus B19 IgM positivity) in susceptible persons (parvovirus B19 IgG-negative or IgM-positive) was common among all 4 groups (23%-30%). This high rate of recent infection occurred during a large community outbreak of fifth disease. Environmental samples collected from a room where a stillborn parvovirus B19-infected fetus was delivered were positive for parvovirus B19 DNA. Thus, this suspected nosocomial outbreak actually reflected transmission outside the hospital, but contaminated environmental surfaces were identified as one potential source for transmission of parvovirus B19.
1994年2月，对某产科病房疑似发生的B19细小病毒医院感染暴发事件进行了调查。研究人员发放了调查问卷，并采集了该产科病房工作人员（n = 91）、同一家医院其他病房工作人员（n = 101）以及附近一家医院产科病房工作人员（n = 81）的血清。献血者（n = 265）作为社区对照。在所有4组人群中，易感人群（B19细小病毒IgG阴性或IgM阳性）近期感染（B19细小病毒IgM阳性）情况较为常见（23%-30%）。这种高近期感染率发生在社区大规模的传染性红斑暴发期间。从一名感染B19细小病毒的死产胎儿分娩所在房间采集的环境样本中，B19细小病毒DNA呈阳性。因此，这次疑似医院感染暴发实际上反映了医院外的传播情况，但已确认受污染的环境表面是B19细小病毒传播的一个潜在来源。
