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四氧嘧啶糖尿病大鼠的血清蛋白和氨基酸模式

Serum proteins and amino-acid pattern in alloxan-diabetic rats.

作者信息

El-Hawary Z, El-Hawary M F, Morcus S R

出版信息

Z Ernahrungswiss. 1977 Dec;16(4):223-6. doi: 10.1007/BF02023699.

DOI:10.1007/BF02023699
PMID:75614
Abstract

Serum total proteins as well as its electrophoretic separated fractions were determined in alloxan-diabetic rats. The total and individual serum amino acids were estimated. Certain abnormalities, with no specific pattern, for total and individual fractions were observed in alloxan-diabetic rats. Most of the free serum amono acids showed low values which was attributed to direct reaction of alloxan with amino acids, urinary loss of amino and/or diverse hormonal and metabolic changes.

摘要

在四氧嘧啶诱导的糖尿病大鼠中测定了血清总蛋白及其电泳分离组分。估算了血清总氨基酸和个别氨基酸的含量。在四氧嘧啶诱导的糖尿病大鼠中观察到总蛋白和个别组分存在某些异常,但无特定模式。大多数游离血清氨基酸值较低,这归因于四氧嘧啶与氨基酸的直接反应、氨基酸的尿流失以及多种激素和代谢变化。

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本文引用的文献

1
A method for the estimation of "true" sugar in 0.05 ml. of blood.一种用于估算0.05毫升血液中“真实”糖分的方法。
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The antidiabetic action of insulin on nitrogen metabolism.胰岛素对氮代谢的抗糖尿病作用。
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3
Role of the Strecker degradation of alpha-amino acid in alloxan diabetes.α-氨基酸的斯特雷克降解在四氧嘧啶糖尿病中的作用。
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Insulin and protein metabolism.胰岛素与蛋白质代谢。
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5
Incorporation of C14-amino acids into protein of isolated diaphragms: an effect of insulin independent of glucose entry.将C14-氨基酸掺入分离膈肌的蛋白质中:胰岛素的一种独立于葡萄糖进入的作用。
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6
The effect of insulin on incorporation of amino acids into protein of normal rat diaphragm in vitro.胰岛素对正常大鼠膈肌体外氨基酸掺入蛋白质的影响。
Biochem J. 1958 Nov;70(3):353-8. doi: 10.1042/bj0700353.
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Paper electrophoresis of serum proteins in control and diabetic rats.对照大鼠和糖尿病大鼠血清蛋白的纸上电泳
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8
Inhibition of muscle glucose uptake by diabetic rat sera of varying glucose and lipoprotein content.不同葡萄糖和脂蛋白含量的糖尿病大鼠血清对肌肉葡萄糖摄取的抑制作用。
J Biol Chem. 1957 May;226(1):459-73.
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Blood keto acid levels during intoxication with inhibitors of carbohydrate metabolism.碳水化合物代谢抑制剂中毒期间的血酮酸水平。
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Effect of diabetes on the concentration of amino acids in plasma and heart muscle of rats.糖尿病对大鼠血浆和心肌中氨基酸浓度的影响。
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