Schwannoma-derived growth factor interacts with the epidermal growth factor receptor.
作者信息
Maher P A, Schubert D
机构信息
Department of Molecular and Cellular Growth Biology, Whittier Institute for Diabetes and Endocrinology; La Jolla, California, USA.
出版信息
J Neurochem. 1995 Oct;65(4):1895-8. doi: 10.1046/j.1471-4159.1995.65041895.x.
Abstract
Schwannoma-derived growth factor (SDGF) is a potent mitogen and neuronal differentiation factor. Because of its relationship to epidermal growth factor (EGF) and the heregulins, it was asked if SDGF interacts with the EGF receptor or HER2/neu. SDGF binds to and causes the phosphorylation on tyrosine of the EGF receptor but not HER2/neu.
摘要
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