来自衰老粘盖牛肝菌子实体的新型羊毛甾烷三萜的结构。

The structures of new lanostane triterpenes from the fruiting bodies of Hebeloma senescens.

作者信息

Garlaschelli L, Vidari G, Virtuani M, Vita-Finzi P, Mellerio G

机构信息

Dipartimento di Chimica Organica, Universita di Pavia, Italy.

出版信息

J Nat Prod. 1995 Jul;58(7):992-1002. doi: 10.1021/np50121a003.

DOI:10.1021/np50121a003

PMID:7561908

Abstract

Three new lanostane triterpenes, hebelomic acids B[4], E[5], and F[6], were isolated from the inedible mushroom Hebeloma senescens. The latter two compounds are acyl derivatives of the new triterpene senescensol (12-deoxycrustulinol) [12]. The structures of compounds 4-6, including the absolute configuration of the 3-hydroxy-3-methylglutaric acid moiety, were established on the basis of spectral and chemical evidence.

摘要

从不可食用的蘑菇衰老疣柄牛肝菌（Hebeloma senescens）中分离出三种新的羊毛甾烷三萜，即衰老疣柄牛肝菌酸B[4]、E[5]和F[6]。后两种化合物是新三萜衰老疣柄牛肝菌醇（12-脱氧硬壳菌素）[12]的酰基衍生物。基于光谱和化学证据确定了化合物4-6的结构，包括3-羟基-3-甲基戊二酸部分的绝对构型。