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充血性心力衰竭、慢性阻塞性肺疾病或糖尿病入院幸存者的院内并发症。

In-hospital complications among survivors of admission for congestive heart failure, chronic obstructive pulmonary disease, or diabetes mellitus.

作者信息

Geraci J M, Ashton C M, Kuykendall D H, Johnson M L, Wu L

机构信息

Houston Center for Quality of Care and Utilization Studies, Houston Veterans Affairs Medical Center, Baylor College of Medicine 77030, USA.

出版信息

J Gen Intern Med. 1995 Jun;10(6):307-14. doi: 10.1007/BF02599949.

Abstract

OBJECTIVE

To determine the frequency of hospital complications among survivors of inpatient treatment for congestive heart failure (CHF), chronic obstructive pulmonary disease (COPD), or diabetes mellitus (DM).

DESIGN

Retrospective cohort study.

SETTING

Nine Veterans Affairs hospitals in the southern United States.

PATIENTS

1,837 men veterans discharged alive following hospitalization for CHF, COPD, or DM between January 1987 and December 1989. This patient population represents a subset of cases gathered to study the process of care in the hospital and subsequent early readmission; thus, veterans who died in the hospital were not included.

MEASUREMENTS

Medical record review to record the occurrence of any of 30 in-hospital complications such as cardiac arrest, nosocomial infections, or delirium (overall agreement between two reviewers = 84%, kappa = 0.37).

RESULTS

Complications occurred in 15.7% of the CHF cases, 13.1% of the COPD cases, and 14.8% of the DM cases. Hypoglycemic reactions were the most frequent individual adverse events in the CHF and DM cases (3.6% and 11.4% of the cases, respectively), and theophylline toxicity was most frequent among the COPD cases (4.9%). Patient age, the presence of comorbid diseases, and the Acute Physiology Score (APS) of APACHE II were associated with complication occurrence. For each disease, the patients who had a complication had significantly longer mean hospital stays than did the patients who did not have complications (14.6 to 14.9 days vs 7.2 to 8.2 days, p < 0.01).

CONCLUSIONS

Complications are frequent among patients discharged alive with CHF, COPD, or DM. The patients who experienced complications were more ill on admission and had longer hospital stays.

摘要

目的

确定因充血性心力衰竭(CHF)、慢性阻塞性肺疾病(COPD)或糖尿病(DM)接受住院治疗的幸存者中医院并发症的发生率。

设计

回顾性队列研究。

地点

美国南部的九家退伍军人事务医院。

患者

1987年1月至1989年12月期间因CHF、COPD或DM住院后存活出院的1837名男性退伍军人。该患者群体是为研究医院护理过程和随后的早期再入院而收集的病例子集;因此,未包括在医院死亡的退伍军人。

测量

通过病历审查记录30种医院并发症中的任何一种的发生情况,如心脏骤停、医院感染或谵妄(两位审查者之间的总体一致性 = 84%,kappa = 0.37)。

结果

CHF病例中有15.7%发生并发症,COPD病例中有13.1%,DM病例中有14.8%。低血糖反应是CHF和DM病例中最常见的个体不良事件(分别占病例的3.6%和11.4%),茶碱中毒在COPD病例中最常见(4.9%)。患者年龄、合并疾病的存在以及急性生理学及慢性健康状况评分系统(APACHE II)的急性生理学评分(APS)与并发症的发生有关。对于每种疾病,发生并发症的患者的平均住院时间明显长于未发生并发症的患者(14.6至14.9天对7.2至8.2天,p < 0.01)。

结论

因CHF、COPD或DM存活出院的患者中并发症很常见。发生并发症的患者入院时病情更严重,住院时间更长。

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