Culora G A, Barnett N, Theaker J M
Department of Histopathology, Southampton General Hospital, U.K.
J Pathol. 1995 Aug;176(4):421-5. doi: 10.1002/path.1711760414.
Eleven cases of chrysiasis have been studied ultrastructurally and by electron probe microanalysis. Tissue samples were examined both with and without osmium and uranyl acetate staining. There was a significant morphological difference in the appearance of the gold deposits within aurosomes between the two groups. The untreated group showed finely granular deposits, often arranged in a linear fashion. Aurosomes from samples treated with osmium and uranyl acetate showed more electron-dense deposits and star-like formations. We propose that treatment of the tissue with osmium and uranyl acetate causes a change in the electron microscopic appearance of aurosomes, including the formation of the characteristic star-like aurosomes.
我们对11例金沉着病进行了超微结构和电子探针微量分析研究。对组织样本进行了有无锇和醋酸双氧铀染色的检查。两组样本中，金质体中金沉积物的外观在形态上存在显著差异。未处理组显示出细颗粒状沉积物，常呈线性排列。经锇和醋酸双氧铀处理的样本中的金质体显示出电子密度更高的沉积物和星状结构。我们认为，用锇和醋酸双氧铀处理组织会导致金质体在电子显微镜下的外观发生变化，包括形成特征性的星状金质体。
