经前症状报告中的遗传和环境因素及其与抑郁和一般神经质特质的关系。

Genetic and environmental factors in premenstrual symptom reporting and its relationship to depression and a general neuroticism trait.

作者信息

van den Akker O B, Eves F F, Stein G S, Murray R M

机构信息

Department of Nursing Studies, Medical School, University of Birmingham, U.K.

出版信息

J Psychosom Res. 1995 May;39(4):477-87. doi: 10.1016/0022-3999(94)00152-u.

DOI:10.1016/0022-3999(94)00152-u

PMID:7562677

Abstract

Previous work has indicated a genetic contribution to premenstrual symptom reporting, regularity and menarche but no genetic contribution to cycle length, and no consistent genetic contribution to premenstrual symptom reporting. This paper reports the results (n = 634) of multivariate genetic analysis in which premenstrual symptom reporting is included in a general personality factor along with extroversion (E), neuroticism (N) and depression (D). The results showed that N, E, D and PMS all fitted on a common personality factor. There was no evidence for a specific genetic contribution of depression or premenstrual symptom reporting over and above those shown in the common personality factor. There were, however, unique/specific environmental contributions for PMS. For E and N, in contrast, both unique genetic and environmental contributions were apparent.

摘要

先前的研究表明，基因对经前症状报告、月经规律性和初潮有影响，但对月经周期长度没有基因影响，对经前症状报告也没有一致的基因影响。本文报告了多变量基因分析的结果（n = 634），其中经前症状报告与外向性（E）、神经质（N）和抑郁（D）一起被纳入一个一般人格因素中。结果表明，N、E、D和经前综合征（PMS）都符合一个共同的人格因素。没有证据表明抑郁或经前症状报告有特定的基因贡献，超出了共同人格因素中显示的那些。然而，经前综合征有独特的/特定的环境贡献。相比之下，对于E和N，独特的基因和环境贡献都很明显。