接触性皮炎中载体蛋白的研究：通过巨噬细胞迁移试验对可溶性表皮载体蛋白进行定位
Studies on carrier protein in contact dermatitis: localization of soluble epidermal carrier proteins by macrophage migration test.
作者信息
Miyagawa N, Miyagawa S, Ishii H, Hayashi K, Sakamoto K, Aoki T
出版信息
Acta Derm Venereol. 1978;58(1):23-7.
The migration of peritoneal exudate cells from picrylchloride-sensitive guinea pigs was inhibited by heteroantigenic components which were isolated by antinormal guinea pig epidermis antibody immunoadsorbent from soluble epidermal proteins of picrylchloride painted guinea pigs. The components were demonstrated by indirect immunofluorescence study to localize in the intercellular spaces of guinea pig epidermis. It is consequently suggested that carrier protein(s) of contact hypersensitivity reside on the cell surface of epidermis.
来自对苦基氯敏感的豚鼠的腹膜渗出细胞的迁移受到异种抗原成分的抑制，这些成分是通过抗正常豚鼠表皮抗体免疫吸附剂从用苦基氯涂抹的豚鼠的可溶性表皮蛋白中分离出来的。通过间接免疫荧光研究证明，这些成分定位于豚鼠表皮的细胞间隙。因此，提示接触性超敏反应的载体蛋白存在于表皮细胞表面。
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