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尼泊尔的I型人类嗜T淋巴细胞病毒以及甲型、乙型和丙型肝炎病毒:一项血清学调查。

Human T-lymphotropic virus type-I, and hepatitis A, B and C viruses in Nepal: a serological survey.

作者信息

Nakashima K, Kashiwagi S, Noguchi A, Hirata M, Hayashi J, Kawasaki T, Uezono K, Itoh K, Acharya G P, Ogata M

机构信息

Department of General Medicine, Kyushu University Hospital, Fukuoka, Japan.

出版信息

J Trop Med Hyg. 1995 Oct;98(5):347-50.

PMID:7563265
Abstract

In 1987, 676 blood samples were collected from inhabitants of the Bhadrakali and Kotyang villages in Nepal. The samples were tested for the prevalence of antibody to hepatitis A virus (anti-HAV), hepatitis B surface antigen (HBsAg), antibody to hepatitis B core antigen (anti-HBc), second-generation antibody to hepatitis C virus (anti-HCV) and antibody to human T-lymphotropic virus type-I (anti-HTLV-I). Anti-HAV was present in 99.3% of the people surveyed. The prevalence of anti-HAV reached 100% in the < 25 age group and was as high or only slightly lower in all other age groups. The prevalence of HBsAg was 0.3% and of anti-HBc 7.7%. Anti-HCV was found in 0.1% of the residents. No significant difference by gender or village was noted in the prevalence of anti-HAV, HBsAg, anti-HBc, or anti-HCV. No anti-HTLV-I-positive persons were identified. These data suggest that the prevalence of hepatitis B and C virus infections in Nepal is low in contrast to hepatitis A virus infection, and that human T-lymphotropic type-I infection may be absent in this population.

摘要

1987年,从尼泊尔巴德拉克利村和科蒂扬村的居民中采集了676份血样。对这些血样进行了甲型肝炎病毒抗体(抗-HAV)、乙型肝炎表面抗原(HBsAg)、乙型肝炎核心抗原抗体(抗-HBc)、丙型肝炎病毒第二代抗体(抗-HCV)和人类嗜T淋巴细胞病毒I型抗体(抗-HTLV-I)的流行率检测。99.3%的受调查者体内存在抗-HAV。在<25岁年龄组中,抗-HAV流行率达到100%,在所有其他年龄组中也同样高或仅略低。HBsAg流行率为0.3%,抗-HBc流行率为7.7%。在0.1%的居民中发现了抗-HCV。在抗-HAV、HBsAg、抗-HBc或抗-HCV的流行率方面,未发现性别或村庄之间存在显著差异。未发现抗-HTLV-I阳性者。这些数据表明,与甲型肝炎病毒感染相比,尼泊尔乙型和丙型肝炎病毒感染的流行率较低,并且该人群中可能不存在人类嗜T淋巴细胞病毒I型感染。

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引用本文的文献

1
Seroprevalence of hepatitis B and C in Nepal: a systematic review (1973-2017).尼泊尔乙型和丙型肝炎血清流行率:一项系统评价(1973 - 2017年)
Hepatol Med Policy. 2018 Sep 6;3:10. doi: 10.1186/s41124-018-0039-2. eCollection 2018.
2
Seroprevalence of HBV and HCV in blood donors: A study from regional blood transfusion services of Nepal.尼泊尔地区输血服务机构对献血者进行的乙肝病毒和丙肝病毒血清学流行率研究。
Asian J Transfus Sci. 2010 Jul;4(2):91-3. doi: 10.4103/0973-6247.67026.